Botox for the esophagus: new hope for swallowing pain?
NCT ID NCT01955174
First seen Jan 05, 2026 · Last updated May 25, 2026 · Updated 26 times
Summary
This study tested whether injecting botulinum toxin (like Botox) into the lower esophagus can relieve chest pain and swallowing difficulty in people with nutcracker esophagus, a condition where the esophagus contracts too strongly. Twenty-four adults with symptoms received either the toxin or a placebo in a double-blind setup. The main goal was to see if symptoms improved enough to lower their Eckardt score below 3.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Service d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot Pavillon H 5 - Hospices Civils de Lyon
Lyon, 69437, France
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Service d'Hépato-Gastro-Entérologie et Oncologie Digestive- Hôpital Haut Lévêque - CHU de Bordeaux
Bordeaux, 33075, France
Conditions
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