Botox tested as potential relief for painful 'Nutcracker' esophagus
NCT ID NCT01955174
Summary
This study tested whether injecting botulinum toxin (Botox) into the lower esophagus could safely reduce symptoms like chest pain and trouble swallowing in people with hypercontractile esophageal disorders. In this small, double-blind trial, 24 participants were randomly assigned to receive either the real injection or a sham procedure. Researchers measured changes in symptom scores, quality of life, and manometry patterns over a 12-month follow-up period to see if the treatment was effective.
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Contacts and locations
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Locations
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Service d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot Pavillon H 5 - Hospices Civils de Lyon
Lyon, 69437, France
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Service d'Hépato-Gastro-Entérologie et Oncologie Digestive- Hôpital Haut Lévêque - CHU de Bordeaux
Bordeaux, 33075, France
Conditions
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