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Botox shot before big hernia surgery may boost recovery

NCT ID NCT07220382

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 26 times

Summary

This study tests whether a one-time Botox injection into the side belly muscles, given 3-7 weeks before open hernia surgery, helps surgeons close the abdominal wall completely. About 188 adults with large ventral hernias will be randomly assigned to get Botox or a placebo shot. The goal is to see if the injection makes surgery easier and leads to fewer complications and a smoother recovery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Main Campus

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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