Botox shot before big hernia op may boost healing
NCT ID NCT07220382
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times
Summary
This study tests whether a one-time Botox injection into the side belly muscles, given 3-7 weeks before open surgery for a large ventral hernia, helps surgeons fully close the abdominal wall. About 188 adults will be randomly assigned to get either Botox or a placebo shot, and neither they nor their doctors will know which. The main goal is to see if the abdomen can be closed without leaving a gap, which may lead to fewer complications and better recovery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Cleveland Clinic Main Campus
RECRUITINGCleveland, Ohio, 44195, United States
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