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New combo attack: fasting diet plus vitamin c may boost immunotherapy in tough colorectal cancer

NCT ID NCT06336902

First seen Jan 07, 2026 · Last updated May 25, 2026 · Updated 18 times

Summary

This early-phase study is testing whether adding a fasting-mimicking diet and high-dose vitamin C to two immunotherapy drugs (botensilimab and balstilimab) is safe and effective for people with a specific type of advanced colorectal cancer (KRAS-mutant). The diet is low in calories and sugar, which may make cancer cells more sensitive to vitamin C. About 15 adults whose cancer has worsened after standard treatments will take part. The main goals are to see if people can stick with the diet and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Los Angeles General Medical Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Jude Medical Center / Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USC / Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.