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New drug combo tested in Hard-to-Treat cancers

NCT ID NCT02211755

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This early-phase trial tested the safety of combining two cancer drugs, bortezomib and clofarabine, in 28 adults with advanced solid tumors, lymphomas, or myelodysplastic syndromes that had stopped responding to standard treatments. Participants received the drugs in 21-day cycles, with close monitoring for side effects and tumor response. The goal was to find the safest dose and see how the drugs affect cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.