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New bone marrow transplant trial offers hope for kids with severe blood disorders

NCT ID NCT03128996

First seen Jan 07, 2026 · Last updated Jun 17, 2026 · Updated 20 times

Summary

This study tests a bone marrow transplant from a family donor for children under 21 with severe non-cancer blood disorders like sickle cell disease, bone marrow failure, or immune problems. The goal is to see if the transplant can replace the diseased cells with healthy donor cells and control the disease. Participants will receive a reduced-intensity conditioning regimen before the transplant to help their body accept the new cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Helen DeVos Children's Hospital

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact

    Contact

  • Nemours Children's Health

    RECRUITING

    Wilmington, Delaware, 19803, United States

    Contact Phone: •••-•••-••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Yale School of Medicine

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact

    Contact

Conditions

The condition(s) this trial relates to.

Bone Marrow Failure Disorders bone marrow failure syndrome disease hemoglobinopathy immune system disorder inherited hemoglobinopathy metabolic disease sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.