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Donor bone vs. your own bone: which works better for jaw repair?

NCT ID NCT07104370

Disease control Sponsor: Semmelweis University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods of rebuilding the jawbone for people who need dental implants but have lost bone after tooth loss. One method uses a piece of the patient's own bone, while the other uses donated, freeze-dried bone. The goal is to see if the donated bone works just as well, with less pain and shorter surgery. Thirty adults who need jaw reconstruction will be randomly assigned to one of the two groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
freeze-dried bone allograft block
What this could lead to
If successful, this could show that freeze-dried bone allografts work as well as the patient's own bone for jaw reconstruction, reducing pain and surgery time.
What could go wrong
This is a small, early-stage trial with only 30 people. Allografts lack living cells, so they may not integrate as well as the patient's own bone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Sep 2033

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * over 18 years old * require lateral augmentation for implant rehabilitation Exclusion Criteria: * Smoking * Pregnancy * Poor oral hygiene * Failure to attend follow-up visits * Therapeutic-dose irradiation to the head and neck region * Local bone tumors, cysts, or inflammatory processes * Decompensated systemic diseases contraindicate surgery * Use of medications affecting bone metabolism (steroids, antiresorptive medications such as bisphosphonates, RANKL inhibitor antibodies, VEGF antagonists) * Psychiatric disorders contraindicate implant rehabilitation

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Edentulous alveolar ridge Edentulous alveolar ridge atrophy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Semmelweis University Department of Public Dental Health

    RECRUITING

    Budapest, Hungary, 1088, Hungary

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