Lying a certain way after brain surgery may stop bleeds returning
NCT ID NCT06401772
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a specific body posture—raising the legs and tilting the head—can prevent chronic subdural hematoma from recurring after surgery. The trial will enroll 830 older adults who have had surgery for this type of brain bleed. Participants will be randomly assigned to follow the posture instructions or receive standard care, and the main goal is to see if the posture reduces the chance of the hematoma coming back.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- body posture (legs elevated, head tilted)
- What this could lead to
- If it works, this simple posture change could become a standard, low-cost way to prevent a dangerous brain bleed from returning after surgery.
- What could go wrong
- This is a behavioral intervention, so results may vary based on how well patients follow instructions. The trial is still recruiting, so it's too early to know if it will be effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 830 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. chronic subdural hematoma is diagnosed with CT/MRI scan; thickness of hematoma is more than 1 cm; 2. more than 60 years of age or 60 years; 3. MGS-GCS (Markwalder's Grading Scale and Glasgow Coma Scale) is less than or equal to 2; 4. patients have neurological symptom caused by CSDH before surgery, such as headache, dizziness, nausea, vomiting, numbness or weakness of limb, instability to walk, unconsciousness, trouble speaking, insensitive, etc. 5. receive burr hole drainage; 6. sign informed consent voluntarily. Exclusion Criteria: 1. have brain hernia or acute massive cerebral infarction that have to perform craniotomy 2. have severe malignancies, hemorrhagic disease, cardiac dysfunction and other serious disease that may impede recovery or follow-up compliance; 3. Spinal deformities (e.g., kyphosis) or psychiatric disorders precluding prolonged body posture therapy adherence 4. Concomitant severe intracranial tumors, aneurysms, or vascular malformations that may impede recovery. 5. Patients with cranial CT demonstrating no significant compression or displacement of brain tissue, asymptomatic presentation, and unaffected daily activities were deemed ineligible for surgical intervention by neurosurgeons; 6. CSDH persisting for over 1 year and exhibiting marked organization/solidification of the hematoma; 7. CSDH caused by over V-P shunting; 8. during burr hole drainage, patients have to perform craniotomy due to acute bleeding or brain hernia; 9. Intraoperative complications (e.g., cerebral contusion, intraparenchymal catheter placement) during burr hole drainage; 10. have deep venous thrombosis of lower extremity or pulmonary embolism; 11. cannot complete regular reexamine within 1 year for any reason; 12. life expectancy less than 1 year; 13. participating other ongoing clinical trial; 14. patients are not qualified for other reason evaluated by two neurosurgeons; 15. have bile reflux gastritis and esophageal diseases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Neurosurgery, Huashan Hospital, Fudan University
RECRUITINGShanghai, Shanghai Municipality, 200000, China
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