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Lying a certain way after brain surgery may stop bleeds returning

NCT ID NCT06401772

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a specific body posture—raising the legs and tilting the head—can prevent chronic subdural hematoma from recurring after surgery. The trial will enroll 830 older adults who have had surgery for this type of brain bleed. Participants will be randomly assigned to follow the posture instructions or receive standard care, and the main goal is to see if the posture reduces the chance of the hematoma coming back.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
body posture (legs elevated, head tilted)
What this could lead to
If it works, this simple posture change could become a standard, low-cost way to prevent a dangerous brain bleed from returning after surgery.
What could go wrong
This is a behavioral intervention, so results may vary based on how well patients follow instructions. The trial is still recruiting, so it's too early to know if it will be effective.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 830 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. chronic subdural hematoma is diagnosed with CT/MRI scan; thickness of hematoma is more than 1 cm; 2. more than 60 years of age or 60 years; 3. MGS-GCS (Markwalder's Grading Scale and Glasgow Coma Scale) is less than or equal to 2; 4. patients have neurological symptom caused by CSDH before surgery, such as headache, dizziness, nausea, vomiting, numbness or weakness of limb, instability to walk, unconsciousness, trouble speaking, insensitive, etc. 5. receive burr hole drainage; 6. sign informed consent voluntarily. Exclusion Criteria: 1. have brain hernia or acute massive cerebral infarction that have to perform craniotomy 2. have severe malignancies, hemorrhagic disease, cardiac dysfunction and other serious disease that may impede recovery or follow-up compliance; 3. Spinal deformities (e.g., kyphosis) or psychiatric disorders precluding prolonged body posture therapy adherence 4. Concomitant severe intracranial tumors, aneurysms, or vascular malformations that may impede recovery. 5. Patients with cranial CT demonstrating no significant compression or displacement of brain tissue, asymptomatic presentation, and unaffected daily activities were deemed ineligible for surgical intervention by neurosurgeons; 6. CSDH persisting for over 1 year and exhibiting marked organization/solidification of the hematoma; 7. CSDH caused by over V-P shunting; 8. during burr hole drainage, patients have to perform craniotomy due to acute bleeding or brain hernia; 9. Intraoperative complications (e.g., cerebral contusion, intraparenchymal catheter placement) during burr hole drainage; 10. have deep venous thrombosis of lower extremity or pulmonary embolism; 11. cannot complete regular reexamine within 1 year for any reason; 12. life expectancy less than 1 year; 13. participating other ongoing clinical trial; 14. patients are not qualified for other reason evaluated by two neurosurgeons; 15. have bile reflux gastritis and esophageal diseases.

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Conditions

The condition(s) this trial relates to.

Hematoma, Subdural, Chronic Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Neurosurgery, Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

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