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A handful of blueberries a day: a new weapon against cognitive decline?

NCT ID NCT05764824

Prevention Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study tests whether taking a daily blueberry powder supplement for 24 weeks can improve memory and other thinking skills in adults aged 65 to 99. Participants will be randomly assigned to receive either the blueberry powder or a placebo, and researchers will measure changes in blood markers associated with brain injury. The goal is to see if this simple dietary addition could help protect the aging brain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Blueberry powder
What this could lead to
If effective, daily blueberry supplementation could offer a simple, natural way to support brain health and potentially slow cognitive decline in aging.
What could go wrong
This is a small, early-stage trial, and results may not be conclusive or generalizable. The benefits might be modest, and the study does not yet prove any effect on dementia or long-term cognitive outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

67 people

The number who actually took part.

Started

Oct 2023

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 99 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 65-99 years * Able to travel to Brigham and Women's Hospital for 4 clinic visits Exclusion Criteria: * Known allergies to blueberries * Unable to abstain from blueberry consumption during the study period * Inability to provide informed consent * Planned major surgery during study period or recent major surgery up to 3 months before recruitment * Organ transplant * Plan to move out of greater Boston area during the study period * Diagnosis of dementia, severe cognitive decline, end-stage renal disease, substance abuse, insulin-dependent diabetes mellitus, major cancer excluding non-melanoma skin cancer, and schizophrenia.

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Conditions

The condition(s) this trial relates to.

brain injury Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain injuries Cognitive decline Nutrition, healthy

Contacts and locations

Locations

  • Mass General Brigham

    Boston, Massachusetts, 02120, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.