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Blueberry showdown: does the whole fruit beat the extract?

NCT ID NCT04329962

Knowledge-focused Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial investigates how well anthocyanins—compounds in blueberries linked to health benefits—are absorbed from two different forms: a blueberry extract confection and a whole blueberry powder confection. Healthy adults will consume each type and provide urine samples to measure the levels of these compounds. The goal is to understand whether the food matrix (whole fruit vs. extract) affects absorption and metabolism, which could inform how best to consume blueberries for potential disease prevention.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
blueberry confections (blueberry extract and whole blueberry powder)
What this could lead to
If it works, this could help clarify how the food matrix affects absorption of beneficial berry compounds, potentially guiding dietary recommendations for disease prevention.
What could go wrong
This is a very small, early-stage study in healthy volunteers, so results may not apply to broader populations or translate into health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

May 2018

Finished

May 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be healthy, free-living adults * Have a body mass index (BMI) between 18 and 35 kg/m\^2 * Be a non-smoker (defined as adults who have never smoked or who have not had a cigarette in the past ten years) * Agree to follow a berry-restricted diet and to document any accidental consumption of restricted foods each day of the study Exclusion Criteria: * Report being actively treated for any metabolic, digestive or immunologic disorder including malabsorptive disorders, renal insufficiency, hepatic insufficiency, any autoimmune disorder or short bowel syndrome * Have a known allergy or food intolerance to ingredients in study products (blueberries), other berries, wheat, or soy * Are strict vegans (no consumption of animal, fish or egg products) * Are planning to conceive, or are currently pregnant or lactating * Are heavy alcohol consumers (defined as an average consumption of greater than 2 drinks/ day) * Have been on an antibiotic regime lasting for one week in the last 6 months

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy diet Nutrition aspect of cancer

Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

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