Can early blood transfusions save more trauma victims?
NCT ID NCT05573841
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study looks at trauma patients with severe bleeding to understand how early blood transfusions affect their chances of survival and blood clotting. Researchers will compare patients who receive a transfusion within two hours of arrival to those who do not, and also examine the impact of giving transfusions before reaching the hospital. The goal is to learn more about the best ways to treat major bleeding after trauma.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood transfusion (erythrocytes, plasma, or whole blood)
- What this could lead to
- If successful, this could help refine transfusion protocols for trauma patients, potentially improving survival and reducing bleeding complications.
- What could go wrong
- As an observational study, it cannot prove cause and effect. Results may be influenced by differences in patient care and may not apply to other trauma centers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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161 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Feb 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All trauma patients admitted to the trauma unit at the Karolinska University Hospital Solna will be studied. Patients receiving unmatched blood (erythrocytes, plasma or whole blood) either in the prehospital phase or during the first two hours of hospital care will be compared to patients not receiving blood products.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All trauma patients admitted to the trauma unit at the Karolinska University Hospital Solna. Exclusion Criteria: * Patients with injuries från hanging, drowning, burns or smoke inhalation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Karolinska University Hospital
Stockholm, 16771, Sweden
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Other studies related to the condition(s) this trial covers.
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