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A simple exercise test may unmask hidden artery damage in CKM syndrome

NCT ID NCT07737561

Knowledge-focused Sponsor: Karamanoğlu Mehmetbey University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study looks at whether blood pressure changes during a routine exercise test can signal stiff arteries in people with Cardiovascular-Kidney-Metabolic (CKM) syndrome. Researchers will measure blood pressure before and after exercise and use ultrasound to check aortic stiffness in 80 adults with CKM syndrome. The goal is to see if the exercise blood pressure response could serve as a simple, non-invasive warning sign for vascular problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, a simple exercise test could help doctors spot hidden artery stiffness in people with CKM syndrome, improving early risk detection.
What could go wrong
This is an observational study, not a treatment trial. It can only show an association, not cause and effect, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adults aged 18 years and older with a diagnosis of Cardiovascular-Kidney-Metabolic (CKM) syndrome who are referred to the cardiology outpatient clinic and scheduled for a clinically indicated exercise stress test as part of routine clinical care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Willing and able to provide written informed consent. * Aged 18 years or older. * Diagnosis of Cardiovascular-Kidney-Metabolic (CKM) syndrome. * Referred by a cardiologist for a clinically indicated exercise stress test as part of routine clinical care. * Able to perform an exercise stress test. Exclusion Criteria: * Physical disability or any medical condition that precludes performing an exercise stress test. * Diagnosis of major depressive disorder

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Conditions

The condition(s) this trial relates to.

cardiovascular-kidney-metabolic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular-kidney-metabolic (CKM) Cardiovascular-kidney-metabolic syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Karaman Training and Research Hospital

    RECRUITING

    Karaman, Turkey (Türkiye)

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