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New transplant approach aims to tame Graft-Versus-Host disease

NCT ID NCT05088356

First seen Jan 04, 2026 · Last updated Jun 16, 2026 · Updated 25 times

Summary

This early-phase study tests a stem cell transplant method for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors give specially selected immune cells (regulatory T-cells) along with regular T-cells to help the body accept the new stem cells while reducing the risk of graft-versus-host disease. The goal is to improve survival and quality of life after transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94304, United States

Conditions

The condition(s) this trial relates to.

acute leukemia acute lymphoblastic leukemia acute myeloid leukemia chronic myelogenous leukemia, BCR-ABL1 positive hematopoietic and lymphoid system neoplasm Leukemia, Myelogenous, Chronic, BCR-ABL Positive mixed phenotype acute leukemia myelodysplastic syndrome Myelodysplastic Syndromes Myeloproliferative Disorders myeloproliferative neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.