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Sound waves open brain barrier to attack deadly tumors

NCT ID NCT04440358

First seen Jan 24, 2026 · Last updated May 01, 2026 · Updated 12 times

Summary

This study tested whether a device using sound waves and microbubbles can safely open the blood-brain barrier in 13 patients with recurrent glioblastoma. The goal was to let more of the chemotherapy drug carboplatin reach the tumor. The study focused on safety and whether the barrier could be opened, not on curing the disease.

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Contacts and locations

Locations

  • Fondazione IRCCS Neurologico Carlo Besta

    Milan, 20133, Italy

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

  • Yonsei University Medical Center

    Seoul, 120-752, South Korea

Conditions

Explore the condition pages connected to this study.