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Mayo clinic tests groundbreaking dual organ transplant for kidney and bladder failure

NCT ID NCT04626167

First seen Apr 23, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This early-phase study at Mayo Clinic is testing whether it is possible to transplant a donor bladder along with a kidney in one surgery. The trial enrolls up to 30 people with chronic kidney disease caused by bladder problems. The goal is to see if the new bladder works well and improves quality of life, while monitoring for side effects and rejection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cadaveric donor bladder and kidney transplant

What this could lead to

If successful, this could offer a new surgical option for people who need both a kidney and bladder replacement, potentially avoiding the use of intestinal tissue for bladder reconstruction.

What could go wrong

This is a very early, small phase 1 trial with only 30 participants. The procedure is complex and carries risks like rejection, infection, and serious side effects. It may not prove safe or effective.

Conditions

The condition(s) this trial relates to.

bladder exstrophy bladder neck obstruction chronic kidney disease chronic renal failure syndrome kidney failure lower urinary tract obstruction, congenital posterior urethral valve urinary bladder disorder Urinary Bladder, Neurogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.