Full bladder technique may boost IUI success
NCT ID NCT07676682
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates whether having a full bladder during intrauterine insemination (IUI) can improve pregnancy rates. The idea is that a full bladder straightens the uterus, making it easier to place sperm correctly using ultrasound guidance. The trial compares this approach to the standard IUI procedure with an empty bladder. Participants are women aged 18–39 with infertility lasting at least a year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bladder filling (full bladder)
- What this could lead to
- If effective, this simple technique could increase pregnancy rates for people undergoing IUI, offering a low-cost improvement to fertility treatment.
- What could go wrong
- This is a single study with 340 participants, and results may not apply to all fertility cases. The technique may cause discomfort or not improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
340 people
The number who actually took part.
- Started
-
Jun 2021
- Finished
-
Nov 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This prospective, randomised, single-centre study was conducted at the Fırat University Department of Obstetrics and Gynaecology, infertility clinic in Elazığ, Turkey, between 01/06/2021 and 03/11/2022.
- Ages
-
18 to 39 years
- Sex
-
Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. The woman is aged between 18 and 39 inclusive. 2. Cases with infertility lasting at least 12 months 3. The presence of known medical indications for IUI. 4. Cases with mild to moderate male factor infertility (cases with a total motile sperm count greater than 5 x 10⁶). 5. Cases with ovulatory disorders 6. Cases diagnosed with unexplained infertility 7. Mixed infertility due to the known causes listed above. 8. Patients who have started primary infertility treatment and those who have started secondary infertility treatment. 9. Cases where ovarian stimulation was performed with gonadotropins. 10. The ability to communicate with the couple verbally or in writing. Exclusion criteria: 1. Cases where unilateral or bilateral tubal passage is absent 2. Cases with acute pelvic inflammatory disease 3. Male partners who have fewer than 1 million motile sperm in semen analysis 4. Endometriosis.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Passive uterine straightening are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Firat Universty
Elâzığ, 23100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Green tea extract may boost fertility in women with fibroids
- Cervical mucus may hold key to unexplained infertility
- Fertility boost? study tests estradiol and guaifenesin alongside clomiphene
- Bee superfood tested as fertility aid for unexplained infertility
- Fertility showdown: ICSI vs IVF – which works better?