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Full bladder technique may boost IUI success

NCT ID NCT07676682

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study investigates whether having a full bladder during intrauterine insemination (IUI) can improve pregnancy rates. The idea is that a full bladder straightens the uterus, making it easier to place sperm correctly using ultrasound guidance. The trial compares this approach to the standard IUI procedure with an empty bladder. Participants are women aged 18–39 with infertility lasting at least a year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bladder filling (full bladder)
What this could lead to
If effective, this simple technique could increase pregnancy rates for people undergoing IUI, offering a low-cost improvement to fertility treatment.
What could go wrong
This is a single study with 340 participants, and results may not apply to all fertility cases. The technique may cause discomfort or not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

340 people

The number who actually took part.

Started

Jun 2021

Finished

Nov 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This prospective, randomised, single-centre study was conducted at the Fırat University Department of Obstetrics and Gynaecology, infertility clinic in Elazığ, Turkey, between 01/06/2021 and 03/11/2022.

Ages

18 to 39 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. The woman is aged between 18 and 39 inclusive. 2. Cases with infertility lasting at least 12 months 3. The presence of known medical indications for IUI. 4. Cases with mild to moderate male factor infertility (cases with a total motile sperm count greater than 5 x 10⁶). 5. Cases with ovulatory disorders 6. Cases diagnosed with unexplained infertility 7. Mixed infertility due to the known causes listed above. 8. Patients who have started primary infertility treatment and those who have started secondary infertility treatment. 9. Cases where ovarian stimulation was performed with gonadotropins. 10. The ability to communicate with the couple verbally or in writing. Exclusion criteria: 1. Cases where unilateral or bilateral tubal passage is absent 2. Cases with acute pelvic inflammatory disease 3. Male partners who have fewer than 1 million motile sperm in semen analysis 4. Endometriosis.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Firat Universty

    Elâzığ, 23100, Turkey (Türkiye)

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