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A scent of citrus: could bitter orange oil ease fatigue and aid sleep in diabetes?

NCT ID NCT07756151

Symptom relief Sponsor: Uludag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests whether inhaling bitter orange oil before bed can improve sleep quality and reduce fatigue in adults with type 2 diabetes. One hundred participants will be randomly assigned to inhale either bitter orange oil or plain water for three nights. On the fourth morning, researchers will measure sleep quality, fatigue levels, and blood sugar to see if the citrus scent makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bitter orange oil inhalation aromatherapy
What this could lead to
If effective, this simple, drug-free aromatherapy could offer a low-cost way to help people with type 2 diabetes sleep better and feel less tired.
What could go wrong
This is a small, short-term trial (three nights) with a subjective outcome. Results may not apply broadly, and the effect could be due to placebo or the ritual of inhalation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * being over the age of 19, * having no communication problem, and voluntarily agreeing to participate in the research, * having been admitted to the clinic at least 24 hours ago, * not having a diagnosed sleep disorder, * not having a psychiatric disorder requiring treatment, * not using narcotic drugs in the last 4 hours, * not eating two hours before going to bed at night, * not being pregnant, * not smoking, * not diagnosed acute rhinitis, sinusitis, or history of loss of smell. Exclusion Criteria: * being under the age of 19, * not being conscious, refusing to participate in the research or opting to leave the study at any point, * having a diagnosed sleep disorder.

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Conditions

The condition(s) this trial relates to.

Fatigue insomnia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes mellitus (T2DM)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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