Bone infection breakthrough? new combo therapy aims to stop chronic osteomyelitis

NCT ID NCT07435051

Not yet recruiting Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study tests whether adding bisphosphonates (a bone-strengthening drug) to the standard antibiotic vancomycin can better control chronic bone infections that are hard to treat. About 280 adults with a specific type of osteomyelitis will be randomly assigned to get either the combination or vancomycin alone after surgery. The main goal is to see if the combination leads to a higher infection control rate at 6 months.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

the Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310000, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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OSTEOMYELITIS (REFRACTORY)