Skin fluid may hold key to early heart disease detection
NCT ID NCT06632353
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether fluid from the skin can be used to detect signs of heart disease. Researchers will collect skin fluid and blood samples from 30 volunteers, including older adults with heart failure and younger healthy adults. The goal is to see if certain biomarkers in skin fluid can help diagnose or monitor cardiovascular conditions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple skin test for early detection of heart disease, potentially allowing for earlier treatment.
- What could go wrong
- This is a very small, early-stage study focused on measuring biomarkers, not treating disease. It may not find reliable markers or translate into a practical test.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2024
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy volunteers and subjects recruited at hospital
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: Group 1: Chronic heart failure with stable therapy. NYHA classification II, III and IV. Age \> 60 years. Group 2: Age 18-40 years. Exclusion criteria: * Participating in another clinical investigation which may affect the study outcome according to clinical judgement. * Previous use of sampling system used. * Pregnancy or lactating. * Any disease or condition that may be affected. * Individuals who lack the ability to fully consent to participate in the study. * Severe skin injury. * Tattoo or piercing close to sampling area. * Group 1: All forms of emergency care. * Group 1: Non-stable therapy. * Group 1: Sepsis. * Group 1: BMI \> 30kg/m2. * Group 1: Age \> 84 years. * Group 2: Known heart or vascular disease. * Group 2: Diabetes. * Group 2: Kidney disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Danderyd Hospital
Danderyd, Sweden
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