Blood test could predict brain inflammation relapses in kids
NCT ID NCT06863974
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times
Summary
This study aims to find blood-based biomarkers that can predict whether a child with acute disseminated encephalomyelitis (ADEM) will experience relapses. Researchers will analyze immune cells from blood samples of 20 children aged 1-18 with a first demyelinating event. The goal is to identify molecular or cellular signatures that indicate a higher risk of recurrence, enabling earlier use of disease-modifying therapies to prevent long-term disability.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Montpellier
NOT_YET_RECRUITINGMontpellier, 34295, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU d'Angers
RECRUITINGAngers, 49240, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Necker Enfants Malades
NOT_YET_RECRUITINGParis, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univesity Hostipal of APHP
RECRUITINGLe Kremlin-Bicêtre, 94270, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univesity Hostipal of Brest
RECRUITINGBrest, 29200, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univesity Hostipal of Nantes
RECRUITINGNantes, 44093, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univesity Hostipal of Rennes
RECRUITINGRennes, 35000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univesity Hostipal of Tours
RECRUITINGTours, 37000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict which children with ADEM will have relapses, allowing earlier treatment to prevent long-term damage.
What could go wrong
This is a small, early observational study with only 20 participants, so findings may not apply to all patients. It looks for patterns in blood, not a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.