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Tooth showdown: which pulp capping material wins?

NCT ID NCT07147036

Disease control Sponsor: Zahoor khan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested two materials, Biodentine and Calcium Hydroxide, placed under fillings to protect the tooth nerve in 76 adults with reversible pulpitis. Over 12 weeks, researchers checked pain, X-ray changes, and nerve responses to see which material better kept the tooth alive and healthy. The goal is to find a more effective way to treat deep cavities without needing a root canal.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Biodentine and Calcium Hydroxide
What this could lead to
If successful, this could show that Biodentine is a better material for preserving tooth vitality and reducing pain after cavity treatment.
What could go wrong
This is a small, completed study with only 76 participants, so results may not apply to everyone. The follow-up is short (12 weeks), so long-term success is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

76 people

The number who actually took part.

Started

Feb 2023

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants must meet all of the following criteria to be included in the study: * Age: 20 to 45 years. * Tooth Type: Mature permanent teeth (maxillary or mandibular). * Caries Status: Occlusal carious lesions without previous restorations. * Pulpal Diagnosis: Reversible pulpitis confirmed by: * Patient history and clinical examination * Positive response to thermal (cold) and electric pulp tests * No tenderness to percussion * Radiographic Assessment: Carious lesion corresponding to ICDAS radiographic score RC-5. * Periapical Status: No signs of periapical radiolucency or root resorption on radiograph. Exclusion Criteria: * Participants will be excluded if they meet any of the following: * Teeth exhibiting signs of irreversible pulpitis or pulp necrosis. * Tenderness to percussion on clinical examination. * Pulp exposure during caries removal. * Systemic conditions that may interfere with healing or immune response, including: Chronic systemic illness Immunocompromised status Pregnancy -Third molars (due to anatomical and treatment variability)

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Reversible pulpitis

Contacts and locations

Locations

  • HITEC-IMS Taxila

    Rawalpindi, Punjab Province, 47080, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.