Heart imaging showdown: which scan guides treatment best?
NCT ID NCT07565805
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is a registry that will enroll 816 adults with coronary artery disease. It compares two types of heart scans—CCTA and OCT—to see which one better identifies dangerous plaque and helps doctors plan treatment. The goal is to improve diagnosis and long-term outcomes, not to test a new drug or device.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 816 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2025
- Expected to finish
-
Dec 2033
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing CCTA and invasive coronary angiography with OCT in native coronary vessels within 3 months
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ≥18 years of age 2. Written informed consent 3. CCTA within 3 months from invasive coronary angiography and OCT 4. At least one vessel with ≥50% diameter stenosis on CCTA 5. OCT performed in native coronary arteries (i.e. pre-PCI or no PCI) Exclusion Criteria: 1. CCTA performed more than 3 months from OCT 2. Poor OCT quality 3. Poor CCTA quality 4. Coronary anomalies 5. Prior PCI or CABG in the vessel imaged with OCT
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Coronary artery disease (CAD) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Department of Cardiology, Bern University Hospital Inselspital
RECRUITINGBern, 3010, Switzerland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Magnetic heart signals could help ER doctors spot hidden heart risk
- Can we predict which heart blockages will worsen after stenting?
- Can a drop of blood predict disease years before it strikes?
- Can a new catheter make heart stenting safer and more effective?
- Heart rehab may tweak cell death pathways — a study investigates
- Can a trained eye match ultrasound for heart stent placement?