Could stimulating both sides of the spine improve bladder control?
NCT ID NCT07505940
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether stimulating nerves on both sides of the lower spine works better than just one side for people with neurogenic bladder—a condition where nerve damage causes bladder control problems. Twenty-nine adults with incomplete spinal nerve injuries will be randomly assigned to try both methods in different orders. The goal is to see if bilateral stimulation reduces incontinence and improves bladder function more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sacral nerve stimulation device
- What this could lead to
- If bilateral stimulation works better, it could offer a more effective way to manage bladder symptoms in people with nerve damage.
- What could go wrong
- This is a small, early-stage trial with only 29 people. It is not yet recruiting, and it is unclear if bilateral stimulation will prove better than the standard unilateral approach.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 29 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. age ≥16 years old; 2. The nerve injury was incomplete injury below grade B, which was diagnosed as neurogenic bladder; 3. Overactive bladder with and/or low compliance bladder (overactive bladder was defined as detrusor contraction during filling, increased intravesical pressure, and early emptying before maximum bladder capacity was reached; Low compliance bladder was defined as loss of the ability to relax during bladder filling, progressive increase of bladder pressure, early emptying of bladder pressure increased, ≤20ml/cmH20). 4. Intermittent catheterization (CIC) can be performed by themselves or CIC can be performed by nursing staff; 5. the patient's physical condition is stable and can be discharged for treatment; 6. Participants voluntarily participated in the clinical study, and they provided written informed consent before the study began Exclusion Criteria: 1. Patients can not perform intermittent catheterization (CIC) by themselves and there is no nursing staff to perform CIC; 2. a history of progressive neurological disorders; 3. abnormal autonomic reflexes; 4. pregnant, lactating women, women of childbearing age who plan to become pregnant during the study period, or who do not use safe contraception; 5. patients with mental and cognitive impairment who are unable to cooperate with surgery and programming; 6. patients have coagulopathy or need anticoagulant therapy and cannot stop the treatment; 7. any serious complications or illnesses that may prevent the patient from participating in or increase the patient's risk of undergoing a surgical procedure; 8. Participants who participated in other clinical trials within 3 months before screening, which may have affected the study results; 9. other conditions considered by the investigator to be inappropriate for study participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Qilu Hospital of Shandong University
Jinan, Shandong, China
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Other studies related to the condition(s) this trial covers.
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