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Can dialysis be personalized? study probes bicarbonate control

NCT ID NCT07779200

Knowledge-focused Sponsor: East and North Hertfordshire NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This observational study looks at factors that influence bicarbonate levels in people on maintenance hemodialysis for end-stage renal disease. Researchers will collect data on demographics, medical history, diet, and dialysis details, and measure bicarbonate levels before and after two dialysis sessions. The goal is to understand how different dialysis methods and individual factors affect acid control, potentially leading to more personalized dialysis prescriptions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
This could help personalize dialysis treatment by tailoring bicarbonate levels to each patient, potentially improving acid control and overall health.
What could go wrong
As an observational study, it can only identify associations, not prove cause and effect. Results may not apply to all dialysis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients with End Stage Renal Disease (ESRD) receiving maintenance dialysis at the study centre.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years and above. * Ability to give informed consent. * End Stage Renal Disease established on maintenance dialysis for at least 3 months. * Patients on dialysis 3 times a week Exclusion Criteria: * Inability to give informed consent * Patients with acute kidney injury * Patients with severe COPD

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Conditions

The condition(s) this trial relates to.

Acidosis end stage renal failure metabolic acidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CKD on hemodialysis patients Metabolic acidosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • East and North Hertfordshire NHS Trust

    RECRUITING

    Stevenage, Hertfordshire, SG1 4AB, United Kingdom

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