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New drug combo shows promise in early cancer trial

NCT ID NCT04282018

First seen Mar 07, 2026 · Last updated Jun 18, 2026 · Updated 17 times

Summary

This early-phase study tested a new drug called BGB-10188, alone or combined with other cancer drugs, in 97 people with certain blood cancers or advanced solid tumors. The goal was to find safe doses and check for side effects. The study was completed, but the ideal dose for some combinations could not be determined due to limited data.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Affiliated Zhongshan Hospital of Fudan University

    Shanghai, Shanghai Municipality, 200032, China

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Blacktown Cancer and Haematology Centre

    Blacktown, New South Wales, 2148, Australia

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200000, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Gallipoli Medical Research Foundation

    Greenslopes, Queensland, 4120, Australia

  • General Hospital of Ningxia Medical University

    Yinchuan, Ningxia, 750004, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450000, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

  • Jining No Peoples Hospital West Branch

    Jining, Shandong, 272000, China

  • Monash Health

    Clayton, Victoria, 3168, Australia

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

  • Perth Blood Institute

    West Perth, Western Australia, 6005, Australia

  • Pindara Private Hospital

    Benowa, Queensland, 4217, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Saint Vincents Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215006, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Third Xiangya Hospital of Central South University

    Changsha, Hunan, 410013, China

  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

  • Zhejiang University College of Medicine Second Affiliated Hospital

    Hangzhou, Zhejiang, 310009, China

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia diffuse large B-cell lymphoma follicular lymphoma Lymphoma, B-Cell, Marginal Zone mantle cell lymphoma marginal zone lymphoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.