New cancer drug combo shows promise but doses remain uncertain

NCT ID NCT04282018

First seen Mar 07, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This study tested a new drug (BGB-10188) alone or with other drugs in 97 people with certain blood cancers or advanced solid tumors. The goal was to find the safest and most effective dose. However, the best dose could not be determined for all groups because not enough data was collected. The study focused on safety and tumor response.

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Contacts and locations

Locations

  • Affiliated Zhongshan Hospital of Fudan University

    Shanghai, Shanghai Municipality, 200032, China

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Blacktown Cancer and Haematology Centre

    Blacktown, New South Wales, 2148, Australia

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200000, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Gallipoli Medical Research Foundation

    Greenslopes, Queensland, 4120, Australia

  • General Hospital of Ningxia Medical University

    Yinchuan, Ningxia, 750004, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450000, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

  • Jining No Peoples Hospital West Branch

    Jining, Shandong, 272000, China

  • Monash Health

    Clayton, Victoria, 3168, Australia

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

  • Perth Blood Institute

    West Perth, Western Australia, 6005, Australia

  • Pindara Private Hospital

    Benowa, Queensland, 4217, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Saint Vincents Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215006, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Third Xiangya Hospital of Central South University

    Changsha, Hunan, 410013, China

  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

  • Zhejiang University College of Medicine Second Affiliated Hospital

    Hangzhou, Zhejiang, 310009, China

Conditions

Explore the condition pages connected to this study.