New hope for tiniest eyes: gentler doses tested for blinding infant condition

NCT ID NCT04634578

Ongoing Disease control Sponsor: Jaeb Center for Health Research Source: ClinicalTrials.gov ↗

Summary

This study is testing whether lower doses of a medicine called bevacizumab can safely and effectively treat a severe eye disease in premature babies. The disease, called retinopathy of prematurity, can cause blindness if not controlled. Researchers are comparing two low-dose injections to see which works best to stop the abnormal blood vessel growth and allow normal eye development.

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Contacts and locations

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Locations

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States
Arkansas Childrens Hospital/ University of Arkansas Medical Sciences

Little Rock, Arkansas, 72202, United States
Boston Children's Hospital

Boston, Massachusetts, 02215, United States
Casey Eye Institute

Portland, Oregon, 97239, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Cincinnati Children's Hospital

Cincinnati, Ohio, 45229, United States
Duke University Eye Center

Durham, North Carolina, 27710, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204-5809, United States
IWK Health Centre

Halifax, Nova Scotia, B3K 6R8, Canada
Indiana University School of Medicine

Indianapolis, Indiana, 46202, United States
Jules Stein Eye Institute at the University of California, Los Angeles

Los Angeles, California, 90095, United States
New York Presbyterian David H Koch Center

New York, New York, 10065, United States
Pediatric Ophthalmology Associates, Inc.

Columbus, Ohio, 43205, United States
Riley Hospital for Children

Indianapolis, Indiana, 46202, United States
Storm Eye Institute

Mt. Pleasant, South Carolina, 29464, United States
Texas Children's Hospital - Dept. Of Ophthalmology

Houston, Texas, 77030, United States
The Emory Eye Center

Atlanta, Georgia, 30322, United States
U of Illinois at Chicago Eye and Ear Infirmary

Chicago, Illinois, 60612, United States
UK Ophthalmology and Visual Sciences, The Eye Clinic

Lexington, Kentucky, 40508, United States
UPMC Children's Eye Center of Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, 15224, United States
Univ of California, Irvine- Gavin Herbert Eye Institute

Irvine, California, 92697, United States
University of California San Francisco Department of Ophthalmology

San Francisco, California, 94143, United States
University of California, Davis

Sacramento, California, 95817, United States
University of Chicago

Hyde Park, Illinois, 60637, United States
University of Utah Moran Eye Center

Salt Lake City, Utah, 84132, United States
Virginia Pediatric Eye Center

Norfolk, Virginia, 23502, United States

Conditions

Explore the condition pages connected to this study.

RETINOPATHY OF PREMATURITY