New hope for tiniest eyes: gentler doses tested for blinding infant condition
NCT ID NCT04634578
Summary
This study is testing whether two lower doses of a medicine called bevacizumab can safely and effectively treat the most severe form of retinopathy of prematurity (ROP), an eye disease in very small premature babies. Doctors are comparing a very low dose (0.063 mg) to the standard low dose (0.25 mg) given as an injection into the eye. The goal is to stop the abnormal blood vessel growth that can lead to blindness, while possibly using less medication.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Arkansas Childrens Hospital/ University of Arkansas Medical Sciences
Little Rock, Arkansas, 72202, United States
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Boston Children's Hospital
Boston, Massachusetts, 02215, United States
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Casey Eye Institute
Portland, Oregon, 97239, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital
Cincinnati, Ohio, 45229, United States
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Duke University Eye Center
Durham, North Carolina, 27710, United States
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Greater Baltimore Medical Center
Baltimore, Maryland, 21204-5809, United States
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IWK Health Centre
Halifax, Nova Scotia, B3K 6R8, Canada
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Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States
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Jules Stein Eye Institute at the University of California, Los Angeles
Los Angeles, California, 90095, United States
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New York Presbyterian David H Koch Center
New York, New York, 10065, United States
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Pediatric Ophthalmology Associates, Inc.
Columbus, Ohio, 43205, United States
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Riley Hospital for Children
Indianapolis, Indiana, 46202, United States
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Storm Eye Institute
Mt. Pleasant, South Carolina, 29464, United States
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Texas Children's Hospital - Dept. Of Ophthalmology
Houston, Texas, 77030, United States
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The Emory Eye Center
Atlanta, Georgia, 30322, United States
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U of Illinois at Chicago Eye and Ear Infirmary
Chicago, Illinois, 60612, United States
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UK Ophthalmology and Visual Sciences, The Eye Clinic
Lexington, Kentucky, 40508, United States
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UPMC Children's Eye Center of Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Univ of California, Irvine- Gavin Herbert Eye Institute
Irvine, California, 92697, United States
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University of California San Francisco Department of Ophthalmology
San Francisco, California, 94143, United States
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University of California, Davis
Sacramento, California, 95817, United States
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University of Chicago
Hyde Park, Illinois, 60637, United States
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University of Utah Moran Eye Center
Salt Lake City, Utah, 84132, United States
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Virginia Pediatric Eye Center
Norfolk, Virginia, 23502, United States
Conditions
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