New study brings opioid addiction treatment to community centers

NCT ID NCT06416020

Disease control Sponsor: Howard University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether offering medication for opioid use disorder (buprenorphine) in community settings—like churches or social service centers—via telemedicine, plus one-on-one coaching, helps people stay in treatment longer than standard clinic care. About 400 participants will be randomly assigned to one of two groups and followed for 24 weeks. The goal is to improve retention and reduce opioid use in high-risk urban neighborhoods.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: buprenorphine
What this could lead to: If successful, this approach could make it easier for people with opioid use disorder to stay in treatment and reduce overdose risk.
What could go wrong: This is an early-stage behavioral study; results may not show a clear benefit, and telemedicine or community support may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Be 16 years of age or older 2. Has been newly prescribed MOUD with buprenorphine by a hub clinic provider no more than 10 days before the day of randomization or on the day of randomization \[Note that the "start" of a "current, new treatment episode" of MOUD with buprenorphine is defined as the date MOUD with buprenorphine was prescribed by a hub clinic provider.\] 3. Is willing and able to provide written informed consent 4. Is willing and able to provide reliable locator information to facilitate contacting the participant for research follow-up assessments 5. Speaks English well enough to be able to comprehend the study procedures and complete the assessments Exclusion Criteria: 1. In the 30 days prior to receiving the prescription for MOUD with buprenorphine from the hub clinic provider, has either taken prescribed MOUD as an outpatient for more than 10 consecutive days OR received injectable MOUD that covers more than 10 consecutive days \[Note that receipt of MOUD in a hospital, residential treatment, or carceral setting would not trigger exclusion.\] 2. Plans to move out of the area or anticipate not being able to remain in the study for 6 months 3. Is currently in jail, prison, or other overnight facility as required by a court of law or have pending legal action that could prevent participation in study activities 4. Has been previously enrolled in CTN-0144 or CTN-0088 or is currently enrolled in another clinical trial for treatment of OUD

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

4 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

New study brings opioid addiction treatment to community centers

What the study statuses mean