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Could a common heart drug spark new muscle growth in babies?

NCT ID NCT04713657

First seen Nov 18, 2025 · Last updated May 17, 2026 · Updated 22 times

Summary

This early-phase trial tests whether the drug propranolol can stimulate new heart muscle cell growth in infants born with Tetralogy of Fallot, a serious heart defect. About 40 babies under 60 days old will receive the drug before routine surgery, and researchers will examine discarded heart tissue for signs of new muscle cells. The goal is to find a way to prevent heart failure later in life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Upmc Children'S Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact

    Contact Email: •••••@•••••

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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