Could a common drug spark heart muscle regrowth in babies with tetralogy of fallot?

NCT ID NCT04713657

First seen Nov 18, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This early-phase study tests whether the drug propranolol can stimulate new heart muscle growth in infants born with Tetralogy of Fallot, a serious heart defect. About 40 babies under 60 days old will receive propranolol, and researchers will measure heart cell division using a special isotope. The goal is to see if this approach can improve heart growth and potentially reduce the risk of heart failure later in life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Upmc Children'S Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact

    Contact Email: •••••@•••••

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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