Heart failure breakthrough? trial tests stopping Beta-Blockers in recovered patients
NCT ID NCT06518694
First seen Jan 24, 2026 · Last updated Jun 23, 2026 · Updated 21 times
Summary
This study tests whether people with heart failure whose heart function has returned to normal can safely stop taking beta-blockers. About 1,300 participants will either gradually stop their beta-blockers or continue them as usual. The goal is to see if stopping the drug leads to a relapse of heart failure or other heart problems, while potentially reducing side effects and medication burden.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hôpital Européen Georges Pompidou
RECRUITINGParis, IDF, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
beta-blockers (discontinued with tapering)
What this could lead to
If successful, this could show that some heart failure patients with normalized heart function no longer need beta-blockers, simplifying their treatment and improving quality of life.
What could go wrong
This is a Phase 3 trial, but it's still uncertain whether stopping beta-blockers is safe. There is a risk of heart failure relapse, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.