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Can berry leaves boost memory? new study tests supplement in seniors

NCT ID NCT06819163

Symptom relief Sponsor: Seppic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a daily berry leaf extract supplement could improve memory, attention, and mood in healthy adults aged 60 to 80 who had minor memory complaints. Over 12 weeks, 109 participants took either the supplement or a placebo. The main focus was on changes in working memory and other cognitive skills.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
berry leaf extract
What this could lead to
If it works, this could point toward a natural supplement to help maintain memory and attention in older adults.
What could go wrong
This is a small, completed study with no phase designation, so results may not be conclusive or generalizable. The effect on cognitive performance may be minimal or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

109 people

The number who actually took part.

Started

Feb 2025

Finished

Oct 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy woman or man * Aged of 60 to 80 years (inclusive) * With self-perceived memory complaints (CDS score ≥ 15) * With a Body Mass Index (BMI) comprised between 18 and 30 kg/m2 (included) * Participants must have completed a minimum of 12 years of formal education, starting from the age of 6. This corresponds to an education level equivalent to the completion of secondary school (e.g., a high school diploma or equivalent) * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Stated willingness to maintain their usual life habits (diet, physical activity, alcohol consumption…) * Speaking French Exclusion Criteria: * Subject with severe medical or cognitive problems which, in the opinion of the Principal Investigator, could interfere with the evaluation of the study criteria or with participant safety * Subject with a MMSE score ≤ 24 * Subject with a coffee consumption of more than 5 cups per day * Subject consuming drugs and/or with historical drug addiction (\<5 years) * Subject with a regular alcohol consumption exceeding 3 standard drinks per day (10 g of pure alcohol each), equivalent to 3 glasses of wine (12 cl), 3 glasses of beer (5°, 25cl), or 3 glasses of spirits (18°, 7 cl) * Smoker or subject consuming regularly products containing nicotine * Subject following a vegetarian or vegan diet * Subject with known hypersensitivity to any component of the study product * Subject who has taken in the 28 days preceding the screening visit or is currently taking drugs or food supplements aiming at improving memory, concentration, sleep, stress, anxiety or other substances which could, in the opinion of the Principal Investigator, interfere with cognitive and emotional processing * Subject participating in another intervention trial

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive performance

Contacts and locations

Locations

  • Center of Investigation in Clinical Nutrition (CICN)

    Louvain-la-Neuve, 1348, Belgium

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