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Beef for brain health? new study tests daily steak against dementia markers

NCT ID NCT07623785

Knowledge-focused Sponsor: South Dakota State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether eating 5.5 ounces of lean beef every day for two weeks can improve blood markers linked to brain health in adults aged 65 and older. Twenty healthy older adults will eat beef for one phase and a non-beef protein source for another, with blood, urine, and stool samples collected to measure changes. The goal is to see if a simple food like beef can help protect against age-related cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lean beef
What this could lead to
If it works, this could point toward a simple dietary change to help preserve memory and brain function in older adults.
What could go wrong
This is a very small, short-term study with only 20 participants. It looks at blood markers, not actual memory or thinking ability, so any benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Adults aged 65 years and older. Generally healthy with no acute illnesses. Fluent in English. Willing to consume lean beef and dairy products (cottage cheese and whey protein) daily during the intervention phases. Willing to maintain current, habitual diet, physical activity levels, and body weight throughout the study. Willing to fast for 12 hours prior to clinical visits and provide blood, urine, stool, and saliva samples. Exclusion Criteria: Diagnosed with Alzheimer's disease, Parkinson's disease, or other severe cognitive disorders. History of gastrointestinal diseases (e.g., Crohn's disease, celiac disease) or major gastrointestinal surgery. Uncontrolled diabetes, severe liver or kidney disease, or a recent cardiovascular event (within the past 6 months). Allergies or severe intolerances to beef or dairy, or adherence to a strict vegetarian or vegan diet. Body weight fluctuation of \>5% within the past 3 months. Use of systemic antibiotics within the 2 months prior to baseline. Current heavy smoking or excessive alcohol consumption.

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Conditions

The condition(s) this trial relates to.

Plaque, Amyloid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain health Cardiometabolic health Cognitive decline prevention in robust older adults Healthy aging Normal aging

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • South Dakota State University

    RECRUITING

    Brookings, South Dakota, 57007, United States

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