Can a simple drink before surgery tame blood sugar spikes in colorectal cancer patients?
NCT ID NCT05494658
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether drinking a mix of branched-chain amino acids (BCAAs) a few hours before colorectal cancer surgery could help prevent high blood sugar afterward. About 79 patients were split into two groups: one got a BCAA drink, the other plain water. The goal was to see if the BCAA group had fewer blood sugar spikes. However, the trial was stopped early, so we don't have clear answers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- branched-chain amino acids (BCAA)
- What this could lead to
- If it worked, this could point toward a simple way to lower blood sugar spikes after colorectal cancer surgery, potentially reducing complications.
- What could go wrong
- The trial was terminated early, so results are limited. It was a small study (79 people) and only tested a short-term effect, so any benefit is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
79 people
The number who actually took part.
- Started
-
Aug 2022
- Finished
-
Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
50 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 50-80 years old ; 2. Clinical diagnosis of colorectal cancer; 3. Planned elective laparoscopic radical resection of colorectal cancer; 4. Preoperative American Society of Anesthesiologists(ASA)score grade I-III ; 5. Informed consent was obtained from patients. Exclusion Criteria: 1. Clinical diagnosis of Diabetes mellitus; 2. Preoperative insulin resistance ; 3. Renal insufficiency requires dialysis, hepatic insufficiency (Child - Pugh grade B and above); 4. Eating disorders caused by gastrointestinal obstruction; 5. Pregnant or lactating women; 6. Patients with severe mental illness.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Colorectal cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shanghai Tongren Hospital
Shanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a lab test tell which chemo works for colon cancer?
- Can MRI and computer models predict how well cancer drugs reach tumors?
- Gut bacteria may hold clues to why some cancer treatments work better
- Burning the edges: a new way to stop colon polyps from coming back
- Missed Follow-Up colonoscopies: do they raise the risk of advanced growths?
- A 2.2 mm scope could spot cancerous tissue in minutes, not days