New pill takes on hard-to-treat KRAS cancers in first human trial
NCT ID NCT06917079
First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 26 times
Summary
This early-phase study tests a new drug called BBO-11818 in adults with advanced lung, pancreatic, or colorectal cancers that have a KRAS mutation. The main goals are to check safety and find the best dose, while also seeing if the drug can shrink tumors. About 387 participants will receive BBO-11818 alone or combined with other cancer treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-••••
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-••••
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Phone: •••-•••-••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-••••
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-••••
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-••••
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-••••
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Sarah Cannon Research Institute at Mary Crowley
RECRUITINGDallas, Texas, 75230, United States
Contact Phone: •••-•••-••••
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The Angeles Clinic and Research Institute - West Los Angeles Office
RECRUITINGLos Angeles, California, 90025, United States
Contact Phone: •••-•••-••••
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-••••
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University of California San Diego Moores Cancer Center
RECRUITINGSan Diego, California, 92037, United States
Contact Phone: •••-•••-••••
Conditions
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