Could a Two-Drug punch shield kidneys from high blood pressure damage?

NCT ID NCT07222917

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 33 times

Summary

This study tests whether adding dapagliflozin to baxdrostat better reduces protein in urine (a sign of kidney damage) than baxdrostat alone in 218 adults with chronic kidney disease and high blood pressure. Participants must already be on stable blood pressure medication. The goal is to see if the combo offers extra kidney protection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

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Surprise, Arizona, 85374, United States
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Hollywood, Florida, 33021, United States
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Port Charlotte, Florida, 33952, United States
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Port Orange, Florida, 32127, United States
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Atlanta, Georgia, 30344, United States
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Champaign, Illinois, 61822, United States
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Wichita, Kansas, 67214, United States
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Eatontown, New Jersey, 07724, United States
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Greenville, North Carolina, 27834, United States
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Jacksonville, North Carolina, 28546, United States
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New Bern, North Carolina, 28562, United States
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Columbus, Ohio, 43215, United States
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Media, Pennsylvania, 19063, United States
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East Providence, Rhode Island, 02914, United States
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Arlington, Texas, 76015, United States
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Pasadena, Texas, 77504, United States
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San Antonio, Texas, 78212, United States
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Woodbridge, Virginia, 22192, United States
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Buenos Aires, C1060AAB, Argentina
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Ciudad de Buenos Aires, C1425AGC, Argentina
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Mar del Plata, 7600, Argentina
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Rosario, S2000CVD, Argentina
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San Nicolás, B2900DMH, Argentina
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Pernik, 2300, Bulgaria
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Plovdiv, 4004, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1680, Bulgaria
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Sofia, 1756, Bulgaria
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Sofia, 1756, Bulgaria
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Yambol, 8600, Bulgaria
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Courtice, Ontario, L1E 2J5, Canada
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Etobicoke, Ontario, M9W 6V1, Canada
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Stouffville, Ontario, L4A1H2, Canada
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Waterloo, Ontario, N2T 0C1, Canada
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Montreal, Quebec, H4J 1C5, Canada
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Anyang-si, 14068, South Korea
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Cheonan-si, 31151, South Korea
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Goyang-si, 10380, South Korea
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Seoul, 04401, South Korea
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Badalona, 08916, Spain
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Pamplona, 31008, Spain
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Valencia, 46010, Spain
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 83301, Taiwan
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New Taipei City, 235, Taiwan
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Taichung, 402, Taiwan
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Taichung, 433004, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 110, Taiwan
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Taoyuan, 333, Taiwan
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Bangkoknoi, 10700, Thailand
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Changwat Sara Buri, 18000, Thailand
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Hat Yai, 90110, Thailand
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Muang, 50200, Thailand
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Ratchathewi, 10400, Thailand
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Adana, 01060, Turkey (Türkiye)
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Adapazarı, 54290, Turkey (Türkiye)
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Kahramanmaraş, 46040, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Kyiv, 01601, Ukraine
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Kyiv, 02002, Ukraine
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Kyiv, 02091, Ukraine
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Kyiv, 03037, Ukraine
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Kyiv, 03049, Ukraine
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Kyiv, 04210, Ukraine
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Uzhhorod, 88018, Ukraine
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Vinnytsia, 21029, Ukraine
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Dundee, DD1 9SY, United Kingdom
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Liverpool, L9 7AL, United Kingdom
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London, E1 1FR, United Kingdom

Conditions

Explore the condition pages connected to this study.

CHRONIC KIDNEY DISEASE AND HYPERTENSION