Could a Two-Drug punch slow kidney disease in High-Risk patients?

NCT ID NCT07222917

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests whether adding dapagliflozin to baxdrostat better reduces protein in urine (a sign of kidney damage) than baxdrostat alone in 218 adults with chronic kidney disease and high blood pressure. Participants must already be on a stable dose of standard blood pressure medication. The goal is to see if the combination offers extra kidney protection.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Surprise, Arizona, 85374, United States
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Hollywood, Florida, 33021, United States
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Port Charlotte, Florida, 33952, United States
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Port Orange, Florida, 32127, United States
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Atlanta, Georgia, 30344, United States
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Champaign, Illinois, 61822, United States
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Wichita, Kansas, 67214, United States
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Eatontown, New Jersey, 07724, United States
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Greenville, North Carolina, 27834, United States
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Jacksonville, North Carolina, 28546, United States
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New Bern, North Carolina, 28562, United States
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Columbus, Ohio, 43215, United States
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Media, Pennsylvania, 19063, United States
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East Providence, Rhode Island, 02914, United States
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Arlington, Texas, 76015, United States
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Pasadena, Texas, 77504, United States
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San Antonio, Texas, 78212, United States
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Woodbridge, Virginia, 22192, United States
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Buenos Aires, C1060AAB, Argentina
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Ciudad de Buenos Aires, C1425AGC, Argentina
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Mar del Plata, 7600, Argentina
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Rosario, S2000CVD, Argentina
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San Nicolás, B2900DMH, Argentina
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Pernik, 2300, Bulgaria
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Plovdiv, 4004, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1680, Bulgaria
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Sofia, 1756, Bulgaria
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Sofia, 1756, Bulgaria
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Yambol, 8600, Bulgaria
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Courtice, Ontario, L1E 2J5, Canada
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Etobicoke, Ontario, M9W 6V1, Canada
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Stouffville, Ontario, L4A1H2, Canada
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Waterloo, Ontario, N2T 0C1, Canada
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Montreal, Quebec, H4J 1C5, Canada
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Anyang-si, 14068, South Korea
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Cheonan-si, 31151, South Korea
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Goyang-si, 10380, South Korea
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Seoul, 04401, South Korea
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Badalona, 08916, Spain
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Pamplona, 31008, Spain
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Valencia, 46010, Spain
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 83301, Taiwan
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New Taipei City, 235, Taiwan
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Taichung, 402, Taiwan
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Taichung, 433004, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 110, Taiwan
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Taoyuan, 333, Taiwan
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Bangkoknoi, 10700, Thailand
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Changwat Sara Buri, 18000, Thailand
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Hat Yai, 90110, Thailand
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Muang, 50200, Thailand
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Ratchathewi, 10400, Thailand
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Adana, 01060, Turkey (Türkiye)
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Adapazarı, 54290, Turkey (Türkiye)
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Kahramanmaraş, 46040, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Kyiv, 01601, Ukraine
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Kyiv, 02002, Ukraine
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Kyiv, 02091, Ukraine
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Kyiv, 03037, Ukraine
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Kyiv, 03049, Ukraine
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Kyiv, 04210, Ukraine
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Uzhhorod, 88018, Ukraine
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Vinnytsia, 21029, Ukraine
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Dundee, DD1 9SY, United Kingdom
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Liverpool, L9 7AL, United Kingdom
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London, E1 1FR, United Kingdom

Conditions

Explore the condition pages connected to this study.

CHRONIC KIDNEY DISEASE AND HYPERTENSION