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Could purging in eating disorders raise cancer risk? new study investigates

NCT ID NCT06532734

Knowledge-focused Sponsor: Denver Health and Hospital Authority Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study aims to see how common Barrett's esophagus is in people with eating disorders who have been purging (vomiting or ruminating) for at least 5 years. Researchers will use a simple, non-endoscopic device called EsoGuard to collect cell samples from the esophagus. The study will enroll 25 adults admitted to a specialized eating disorder center. Results could help decide if current screening guidelines should be expanded for this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds a link, it could lead to better screening guidelines for Barrett's esophagus in people with eating disorders who purge.
What could go wrong
This is a very small pilot study (25 people) and only looks at one group. It may not apply to everyone with eating disorders, and it won't test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ACUTE patients with a confirmed dx of AN-BP, with a purging history of \>5 year, with a frequency of purging of at least once a day.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with an eating disorder diagnosis that includes purging history * Ages 18-65 * Purging history =\>5 years * Purging or rumination at a minimum of once daily upon admission. * Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition Exclusion Criteria: * Any eating disorder diagnosis that does not include purging behaviors * Ages under 18 and over 65 * Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background) * Received mandated care at time of enrollment * Inability to consent to participate in the research

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus anorexia nervosa Barrett esophagus binge eating disorder bulimia nervosa eating disorder esophageal adenocarcinoma Feeding and Eating Disorders rumination disorder Rumination Syndrome Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa, binge eating/purging type Barrett esophagus Eating disorders Esophageal adenocarcinoma Rumination Vomiting

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ACUTE Center for Eating Disorders and Severe Malnutrition

    RECRUITING

    Denver, Colorado, 80204, United States

  • Denver Health and Hospital Authority

    RECRUITING

    Denver, Colorado, 80204, United States

  • Denver Health and Hospital Authority

    RECRUITING

    Denver, Colorado, 80204, United States

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