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Could your gut bacteria predict colon Cancer's return?

NCT ID NCT07211230

Knowledge-focused Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether certain bacteria in your stool can help predict if colon cancer will come back after surgery. Researchers will collect stool and blood samples from 107 adults before and after their surgery. They want to see if bacteria that break down collagen are linked to cancer returning, especially in people with certain diets. This is an observational study, not a treatment, and aims to better understand the role of bacteria in cancer recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 107 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients undergoing Colorectal Surgery

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English speaking. * All genders, races, and ethnicities. * Aged greater or equal to 18 years of age. * Ability to understand and the willingness to sign a written informed consent form. * Diagnosed with a colon adenocarcinoma or presumed adenocarcinoma in which surgical resection is recommended. * Have a planned surgical resection of the colon adenocarcinoma at the University of Chicago Comprehensive Cancer Center. * Reside within 150 miles of the University of Chicago Comprehensive Cancer Center. Exclusion Criteria: * Stage IV colon adenocarcinoma (known metastatic disease). * Intravenous or oral antibiotic exposure within 30 days of surgery to treat an infection. * Prebiotic exposure within 30 days of surgery. * History of neoadjuvant chemotherapy/radiation to treat the primary colon adenocarcinoma. * History of chemotherapy/radiation to treat a separate malignancy within the last 6 months. * History or current ileostomy or colostomy. * Allergy to perioperative medications (oral neomycin/metronidazole for preoperative bowel preparation, intraoperative prophylactic intravenous cefoxitin). * Patients who are pregnant. * Patients with a history of inflammatory bowel disease. * Patients with a history of bariatric surgery. * History of eating disorders.

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Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colonic neoplasm colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal (colon or rectal) cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.