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Engineered immune cells aim to stop bone cancer in its tracks

NCT ID NCT07428993

First seen Feb 26, 2026 · Last updated Jun 06, 2026 · Updated 17 times

Summary

This study tests whether a special type of immune cell, called B7-H3-CAR T cell, can help prevent bone cancer from returning in children with high-risk osteosarcoma. Participants receive the cells after completing standard chemotherapy. The goal is to see if this approach improves how long children stay cancer-free and overall survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105-2794, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

osteosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.