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New hope for melasma: azelaic acid matches hydroquinone?

NCT ID NCT07327983

First seen Jan 09, 2026 · Last updated May 20, 2026 · Updated 21 times

Summary

This study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors tracked changes in patch size and darkness. The goal was to see if azelaic acid works as well as hydroquinone with fewer side effects.

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Contacts and locations

Locations

  • Gujranwala Medical College Hospital

    Lahore, Punjab Province, +92, Pakistan

Conditions

Explore the condition pages connected to this study.