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New combo pill shows promise for lowering stubborn high cholesterol

NCT ID NCT06742853

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 31 times

Summary

This early-stage study tested a new drug called AZD0780 in 81 healthy adults with high LDL (bad) cholesterol. Participants took AZD0780 or a placebo on top of standard cholesterol medicines like ezetimibe, rosuvastatin, or bempedoic acid. The main goals were to see how well the combination lowers cholesterol and whether it is safe. Since high cholesterol requires ongoing management, this is not a cure but a potential new treatment option.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Glendale, California, 91206, United States

  • Research Site

    Brooklyn, Maryland, 21225, United States

  • Research Site

    Harrow, HA1 3UJ, United Kingdom

Conditions

Explore the condition pages connected to this study.