New combo pill for high cholesterol shows promise in early trial

NCT ID NCT06742853

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This early-stage study tested a new drug called AZD0780 in 81 adults with high LDL ("bad") cholesterol. Participants took AZD0780 or a placebo on top of their usual cholesterol medicines like ezetimibe or statins. The goal was to see if AZD0780 safely lowers LDL more than placebo when added to these treatments.

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Contacts and locations

Locations

  • Research Site

    Glendale, California, 91206, United States

  • Research Site

    Brooklyn, Maryland, 21225, United States

  • Research Site

    Harrow, HA1 3UJ, United Kingdom

Conditions

Explore the condition pages connected to this study.