New drug shows promise for reducing narcolepsy attacks over the long term
NCT ID NCT05113745
First seen Nov 14, 2025 · Last updated Jun 15, 2026 · Updated 33 times
Summary
This study looked at the long-term safety and effectiveness of a drug called AXS-12 for people with narcolepsy who also have sudden muscle weakness (cataplexy) and severe daytime sleepiness. 68 people who had already completed an earlier study took AXS-12 and were monitored for side effects and changes in how often they had cataplexy attacks. The goal was to see if the drug remains safe and helpful over time.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinical Research Site
Phoenix, Arizona, 85054, United States
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Clinical Research Site
Boulder, Colorado, 80301, United States
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Clinical Research Site
Colorado Springs, Colorado, 80918, United States
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Clinical Research Site
Brandon, Florida, 33511, United States
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Clinical Research Site
Clearwater, Florida, 33765, United States
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Clinical Research Site
Doral, Florida, 33122, United States
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Clinical Research Site
Miami Lakes, Florida, 33016, United States
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Clinical Research Site
Winter Park, Florida, 32789, United States
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Clinical Research Site
Atlanta, Georgia, 30315, United States
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Clinical Research Site
Atlanta, Georgia, 30328, United States
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Clinical Research Site
Stockbridge, Georgia, 30281, United States
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Clinical Research Site
Chevy Chase, Maryland, 20815, United States
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Clinical Research Site
Kalamazoo, Michigan, 49008, United States
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Clinical Research Site
Novi, Michigan, 48377, United States
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Clinical Research Site
Neptune City, New Jersey, 07753, United States
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Clinical Research Site
Denver, North Carolina, 28037, United States
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Clinical Research Site
Gastonia, North Carolina, 28054, United States
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Clinical Research Site
Huntersville, North Carolina, 28078, United States
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Clinical Research Site
Cincinnati, Ohio, 45245, United States
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Clinical Research Site
Wyomissing, Pennsylvania, 19610, United States
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Clinical Research Site
Charleston, South Carolina, 29425, United States
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Clinical Research Site
Columbia, South Carolina, 29201, United States
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Clinical Research Site
Austin, Texas, 78731, United States
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Clinical Research Site
San Antonio, Texas, 78229, United States
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Clinical Research Site
Toronto, Ontario, M5S 3A3, Canada
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.