New hope for japanese patients with Hard-to-Treat chronic GVHD
NCT ID NCT06263478
First seen Jan 11, 2026 · Last updated May 27, 2026 · Updated 19 times
Summary
This study tests a drug called axatilimab in Japanese patients with chronic graft-versus-host disease (cGVHD) that has not improved after at least two prior treatments. cGVHD is a complication of stem cell transplants where donor cells attack the patient's body. The goal is to see if axatilimab can control the disease and improve symptoms. About 21 participants aged 6 and older will take part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Fujita Health University Hospital
Aichi, 470-1192, Japan
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Hiroshima University Hospital
Hiroshima, 734-8551, Japan
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Hokkaido University Hospital
Hokkaido, 060-8648, Japan
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Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital
Nagoya, 453-8511, Japan
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Kobe City Medical Center General Hospital
Hyōgo, 650-0047, Japan
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Kyushu University Hospital
Fukuoka, Japan
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National Center For Child Health and Development
Tokyo, 157-8535, Japan
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National Hospital Organization Kumamoto Medical Center
Kumamoto, 860-0008, Japan
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Okayama University Hospital
Okayama, 700-8558, Japan
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Osaka Metropolitan University Hospital
Osaka, 545-8586, Japan
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Osaka Prefectural Hospital Organization Osaka International Cancer Institute
Osaka, 541-8567, Japan
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Saitama Prefectural Children'S Medical Center
Saitama-shi, Saitama,, 330-8777, Japan
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Tohoku University Hospital
Miyagi, 980-8574, Japan
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Tokai University Hospital
Kanagawa, 259-1193, Japan
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Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
Tokyo, 113-8677, Japan
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University of Fukui Hospital
Fukui, 910-1193, Japan
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.