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New combo therapy aims to tame stubborn transplant complication

NCT ID NCT06663722

First seen May 15, 2026 · Last updated May 22, 2026 · Updated 2 times

Summary

This study tests whether combining the drug axatilimab with a blood-filtering treatment called ECP can help people with chronic graft-versus-host disease (cGVHD), a condition where donor immune cells attack the recipient's body after a stem cell transplant. About 49 participants aged 12 and older who have not responded to at least two prior treatments will receive the combination. The main goal is to see how many achieve a partial or complete response, while also tracking side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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