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New drug combo aims to wipe out Hard-to-Treat blood cancers

NCT ID NCT04941716

First seen Nov 19, 2025 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This study tests a combination of two drugs, acalabrutinib and venetoclax, in people whose chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) has returned or not responded to prior therapy. The goal is to see if the combination can kill more cancer cells and achieve very deep remissions. About 20 adults with active disease will take both drugs by mouth. This is not a cure, but aims to control the disease and improve outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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