Scientists probe the Brain's brakes: can attention control inhibition?

NCT ID NCT04279158

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates how attention influences the brain's ability to inhibit or stop actions. Researchers will test 120 participants, including healthy volunteers and people with conditions like ADHD or stroke-related neglect, using computer-based tasks that measure eye and hand movements. The goal is to develop a better theoretical model of attention and inhibition, which could improve future diagnostic and rehabilitation tools.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to: If successful, this research could lead to better diagnostic tools and rehabilitation methods for conditions like ADHD or stroke-related neglect.
What could go wrong: This is an early-stage observational study, not a treatment trial. Results may not directly translate into clinical practice or benefit participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2022

Expected to finish

Nov 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

All patients and healthy subjects: Inclusion Criteria: * male and female, age from 18 to 75 years included * normal vision or corrected vision * covered by social security * signed written informed consent Exclusion Criteria: * unable to comply with requirements of the study (neurological, psychiatric, sensory or motor troubles) * adults under legal protection Patient with hemispatial neglect: Inclusion Criteria: * After a stroke (\> 1 month ago), presence of a neurological impairment documented by brain imaging (standard of care) and by clinical symptoms. * The diagnosis will be dissociated from hemianopia by perimetry. The hemispatial neglect consists of a lack of perception and responsiveness concerning the controlesional visual hemifield. Patient with optic ataxia: * After a stroke (\> 1 month ago), presence of neurological injury in parietal cortex only, supported by a standard of care cerebral MRI * Present optic ataxia symptoms (The OA consists of pointing errors with the hand contralateral to the lesion (hand effect) and / or to visual targets presented in the field contralateral to the lesion (field effect)). Patient (adult and children) with attention-deficit hyperactivity disorder: * present a diagnosis of ADHD subtype inattention or impulse / hyperactivity as established by a neuropsychologist. * Children will be between 8 and 18 years old * Adults will be between 18 and 75 years old. * Participants will not report any comorbid learning disabilities to ADHD. For minors: \- Having obtained the written consent of the legal representative(s) Healthy subjects Inclusion Criteria: \- no known neurological injury

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Attention deficit hyperactivity disorder are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder Balint syndrome Inhibition, Psychological perceptual disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Optical phenomena

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

Open the record ↗
A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Scientists probe the Brain's brakes: can attention control inhibition?

What the study statuses mean